Multifunctional siRNA Delivery System for Cancer Therapy

نویسندگان

  • O. Taratula
  • R. Savla
  • I. Pandya
  • H. Geng
  • A. Wang
  • T. Minko
  • H. He
چکیده

The rationale for this study is to develop a multifunctional nanomedicine platform for siRNA targeted delivery to cancerous tumors as well as the use of MRI as a non-invasive strategy to monitor the drug therapy outcome. Therefore, we propose a novel multifunctional gene delivery vector by combining the magnetic properties of iron oxide nanoparticles and their ability to package siRNA strands into discrete nanoparticles.

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تاریخ انتشار 2008